The best case is going to be the one that covers your needs the best. There are lots to choose from.
There are a number of us that are waiting on the Lifeproof.com cases. Steep at 69.99, but waterproof, dust proof, and shock proof - to about 2 meters (for water and shock)
Incase, Seideo and Boxwave are other good case companies.
If you are looking for a hardcore band, baseonelabs is a good bet.
I'm a carpenter and I have the Otterbox. I also had the Otterbox for my blackberry did not have one for my droid but the droid was tuff. But so far I trust the Otterbox. But a dust proof case and water proof that will rock.