So does the phone charge from the same cable connected to the wall charger? If so, I would try to reinstall iTunes latest version and test.
What operating system are you using? Windows XP, VIsta, MAC?
If a windows system, does the system make the "hardware Connected" tone notification when you plug in your phone? Does a window open up asking what you would like to do with "Apple iPhone Camera" pictures? if all that is happening, then it's something in iTunes. If not, then there might be a problem with the phone's connector. Make sure that it is debris free. No lint or anything. Blow it out with straw or something. don't use canned air. It could blow crap up into the phone.
If none of that works, the last suggestion is to test on somone elses PC to see if it is recognized. If not, take it to Apple.